Unlike other AT-II-receptor blockers, losartan has a uricosuric ... as a single-ingredient product and in combination with hydrochlorothiazide (Hyzaar, Merck; losartan potassium 50 mg plus ...

It has been assumed that β-AR antagonists (β-blockers) have a direct favorable influence on the heart, but our results challenge this view, suggesting that β-blockers may also act directly in ...