To meet predefined lowdensity lipoprotein-cholesterol (LDL-C) target levels, atorvastatin dosages were increased to 20mg or 40mg once daily after 8 and 16 weeks, respectively. Results: After 52 ...
Your body makes cholesterol naturally through the liver and other organs. The foods you eat also may contain cholesterol. What your doctor advises on cholesterol levels may depend on many factors ...
AstraZeneca is to sell European rights to its cholesterol drug Crestor (rosuvastatin) to Germany’s Grunenthal. Crestor is a statin and at its peak generated annual revenues of more than $7 ...
Verve Therapeutics has started dosing patients in a phase 1b trial of its in vivo gene-editing drug for high cholesterol, designed to permanently switch off the PCSK9 gene with a one-shot treatment.
Odds ratio was 2.59 (without statins: 0.62; with statins: 1.48; p = 0.002). Patients treated with atorvastatin and simvastatin were compared (the number of patients taking other statins was too ...
Licensed from Novartis, MAR001 is a potential first-in-class antibody. While commonly used statins are effective at lowering LDL cholesterol and triglycerides, MAR001 targets ANGPTL4, a protein highly ...
Unfortunately, a statistical model has not yet been developed that incorporates the uncertainty of the net benefit of the drug, such as the CI of the HR, into a postponement model. Consequently, there ...