Understanding how patients with heart failure with preserved ejection fraction (HFPEF) die provides insight into the natural history and pathophysiology of this complex syndrome, thereby allowing ...

Novel therapies for HFmrEF and HFpEF aim to improve symptom management and patient outcomes, addressing current treatment limitations. Emerging treatments could reduce hospitalization rates and ...

Background: The incidence of HFpEF in women significantly escalates following the age of menopause. This trend cannot solely be attributed to chronological aging, as evidenced by the more gradual ...

The purpose of this study is to look at the differences in how individuals with HFpEF-CKD and HFpEF-EI’s bodies function using Sacubatril/valsartan (Entresto 97/103 mg), which is FDA approved for the ...

Heart failure with preserved ejection fraction (HFpEF) is a growing concern in cardiovascular medicine; representing over 50% of patients diagnosed with heart failure. Despite its growing prevalence, ...

Background: Transition from fatty acid oxidation to glycolysis is linked to oncometabolism and cardiac hypertrophy. We hypothesize that such a metabolic shift is pivotal in driving HFpEF in 3 murine ...

Background HFpEF is often diagnosed in elderly patients coupled with comorbidities and degrees of frailty. Given the lack of evidence-based therapies, the common maxim is to ‘optimize comorbidities ...

Objective: To provide an overview of heart failure with preserved ejection fraction (HFPEF), as well as its pathophysiology, diagnosis, and clinical evidence regarding its pharmacologic management.

About half of all people with heart failure have a heart that pumps normally—or at near-normal levels. Heart failure with preserved ejection fraction (HFpEF), also known as diastolic heart failure, ...

The trial was done in adults with obesity and heart failure with preserved ejection fraction (HFpEF). The data, posted online on August 1, has not yet been published in a peer-reviewed journal.

However, the application of MRAs in patients with heart failure and mildly reduced ejection fraction (HFmrEF) or heart failure and preserved ejection fraction (HFpEF) has remained an area of ...