Steroidal mineralocorticoid receptor antagonists lower mortality in patients with heart failure and reduced ejection fraction (HFrEF), but more data are needed about nonsteroidal mineralocorticoid ...

The American College of Cardiology (ACC) and the American Heart Association (AHA) recommend that cardiologists manage heart failure by its stage: There is no cure for HFpEF, but timely management ...

MRA use reduces CV and all-cause death in HFrEF trials but not in the HFmrEF/HFpEF trials. MRA use increases the risk for hyperkalemia, but absolute risk of severe hyperkalemia is low. This is an ...

Introduction: Heart failure with preserved ejection fraction (HFpEF) is a heterogenous clinical syndrome that accounts for nearly half of all heart failure cases world-wide. The pathophysiological ...

Novel therapies for HFmrEF and HFpEF aim to improve symptom management and patient outcomes, addressing current treatment limitations. Emerging treatments could reduce hospitalization rates and ...

Background: Transition from fatty acid oxidation to glycolysis is linked to oncometabolism and cardiac hypertrophy. We hypothesize that such a metabolic shift is pivotal in driving HFpEF in 3 murine ...

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The ACC released its 2024-25 men’s basketball schedule on Tuesday, with an emphasis on the league’s projected frontrunners, as well as its three new members. Each of the conference’s now-18 ...

The status-quo is unsustainable, and FSU is worth more than the $41 million in media rights revenue it's paid annually under the current ACC contract with ESPN that goes through 2036. Well ...

The role of ACE inhibitors in the management of HFPEF is less significant compared with their role in the management of heart failure with left ventricular systolic dysfunction. For patients with ...