An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.

On the walls I hang push brooms, apple pickers, walnut pickers, drywall sanders, safety harness, folding sawhorses, stepladders, folding work benches, plumber’s snakes and electrical extension cords ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Genomes are organised into DNA loops by the ...

Every shop needs a set of saw horses. Often thought of as just a crossbeam supported by four A-frame legs, saw horses are ...