Pyroptosis is a form of programmed cell death that is crucial in the development of various diseases, including autoimmune diseases, atherosclerotic diseases, cancer, and pregnancy complications. In ...
The findings were recently published in Communications Chemistry. p53 is central to the body's defense against cancer, tasked with regulating the cell cycle and triggering the death of damaged ...
Missense mutations in the p53 DNA-binding domain (DBD) contribute to half of new cancer cases annually. Here we present a thermodynamic model that quantifies and links the major pathways by which ...