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Key proteins, such as suppressor of cytokine signaling (SOCS3) and protein-tyrosine phosphatase 1B ... Leptin and Insulin ...

Co-opted pathways required by oncogenic KRAS in order to sustain lung tumorigenesis Cytokine signaling and its associated STAT3 and NF-κB activation are required for KRAS-induced tumorigenesis.

In ex vivo primary cell models, the authors demonstrated that p300 KAT inhibition by KB-7898 modulated proinflammatory ...

Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for ...

Ototoxicity, characterized by hearing loss and other auditory disturbances, is a significant adverse effect associated with ...

These risk factors can, in turn, activate intracellular signal pathways such as phosphatidylinositol 3-kinase (PI3K)/Akt, mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase ...

Professor Nancy Ip discusses her groundbreaking neuroscience research, focusing on neurotrophic factors and innovative ...

Our proprietary multi-cytokine platform generates rationally designed composite peptides that selectively ... Itolizumab: a monoclonal antibody that targets the CD6-ALCAM signaling pathway which plays ...

Genetic, molecular, and computational analyses reveal that salt stress alters root apical meristem size through miR165/166-mediated regulation of cytokinin levels via the PHB-IPT7 pathway.

Equillium, Inc. (Nasdaq: EQ), a clinical-stage biotechnology company leveraging a deep understanding of immunobiology to ...