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哪类降糖药物与2型糖尿病患者痴呆风险降低有关?
随着2型糖尿病管理的逐年优化,患者预期寿命不断延长,痴呆已经被视为2型糖尿病的一种远期并发症并受到学界重视。2型糖尿病可通过诱导慢性高糖毒性、脑细胞胰岛素抵抗、系统性炎症状态及颅内血管内皮损伤等多种机制引起患者痴呆风险增加。流行病学研究提示2型糖尿病患者发生痴呆的风险显著高于健康人群,且校正血糖、大血管 ...
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