编者按：人类使用卡介苗（BCG）疫苗的历史已有百余年，但对其预防同源（结核分枝杆菌）或异源（如流感病毒）感染的保护能力的理解仍然有限。本期“结核之窗”栏目中，卢水华教授团队将分享一项发表于《自然-免疫学》（Nat ...

Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, United States; ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

1Department of Clinical Laboratory, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, China. 2Zhejiang Key Laboratory of Tumor Molecular Diagnosis and ...

Lm was measured independently by two researchers in a blinded fashion. Surface proteins and cytokines of lung T cells were analyzed by flow cytometry using antibodies against CD3, CD4, IFN-γ, TNF-α, ...

Background and objectives: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease involving the spine, peripheral joints, and entheses. Functional impairment of regulatory T cells (Treg) is ...

Objective Accumulation of mitochondria underlies T-cell dysfunction in systemic lupus erythematosus (SLE). Mitochondrial turnover involves endosomal traffic regulated by HRES-1/Rab4, a small GTPase ...

Background Genomic screening uncovered interferon-gamma (IFNγ) pathway defects in tumours refractory to immune checkpoint blockade (ICB). However, its non-mutational regulation and reversibility for ...