T cells are a type of white blood cell that is central to your immune defense. There are four types which serve different functions: This article will guide you through how CD4 and CD8 cells interact, ...

“Most notably, we will be showcasing what we believe to be the first iPSC-derived CD4+ and CD8+ CAR T cells that demonstrate function comparable to primary αβ CAR-T cells. The engineerability of ...

Combining the molecular signatures with immunophenotypic profiles revealed that cytotoxic CD8 ­T cells­ were associated with SGS. Further, we observed the activation of SGS in cytotoxic CD8 T cells ...

The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of ...

The development of CAR-T cell therapy marks a major breakthrough in cancer treatment. These “living drugs” are T-cells genetically engineered to spread through the body, identify, and destroy cancer ...

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion ...

Construction of CAR or other engineered T cell receptors - Traditional and innovative CAR structural designs - Practical aspects of screening and manufacturing CAR therapies - Feasibility studies in ...

In a recent study published at *Cell Reports Medicine*the team identified three key success markers: the CD4:CD8 ratio, exhaustion signals and the expansion of gamma-delta cytotoxic T-cells. Taken ...

In a recent study published at Cell Reports Medicine the team identified three key success markers: the CD4:CD8 ratio, exhaustion signals and the expansion of gamma-delta cytotoxic T-cells.