Consequently, a thorough understanding of the alterations of TME and the identification of upstream regulatory targets have emerged as a research priority. NF-κB transcription factors, central to ...

This contrasts with the diverse activated CD8+ T cells found in responders. Furthermore, tumor cells in non-responders frequently showed heightened transcriptional activity in the NF-kB and STAT3 ...

The unlabeled cells (hDPSCs) and CD14 + cells (macrophages) were collected separately and pelleted at 300 x ... However, cell-to-cell contact appears to have a stronger influence, as evidenced by its ...

However, CD14 expression in adipocytes could also be responsible for these effects because glucose intolerance did not worsen in CD14 KO mice grafted with bone marrow stem cells from WT mice fed ...

FAM76B has been reported to be a nuclear speckle-localized protein with unknown function. In this study, FAM76B was first demonstrated to inhibit the NF-κB-mediated inflammatory pathway by affecting ...