But it only worked when sleep was natural. Anesthesia and sleeping pills shut this process down nearly completely. The glymphatic system in the brain was discovered back in 2013 by Dr. Maiken ...

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In 2012, neuroscientist Maiken Nedergaard from the University of Rochester Medical Center (URMC) described a unique system used by the brain to rid itself of waste. Termed the "glymphatic system ...

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A specialized system sends pulses of pressure through the fluids in our brain.

In other words, “their brain doesn’t get cleaned very well”, says Nedergaard. Although the experiment tested zolpidem, nearly all sleeping pills inhibit the production of norepinephrine.