Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression. A new study led by The ...

People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...

A new study in mice explains how even a single faulty copy of the BRCA1 gene can fuel tumor growth. The findings suggest the dominant “two-hit” hypothesis of cancer development may not tell the full ...

The new research led by UT Health San Antonio shows that BRCA1 not only pushes a DNA break toward an accurate DNA repair mechanism called homologous recombination (HR) but also promotes subsequent ...

University of Oregon biologists have uncovered a mechanism by which a well-known breast cancer gene also influences fertility ...

People inherit two copies of each gene — one from each parent — an evolutionary fail-safe to ensure survival even when one of ...

Reseachers from WEHI (Melbourne, Australia) have found a new way to predict a subset of patients who are likely to become ...

TOP1 is the target of topotecan, which was approved in 1997 by the U.S. Food and Drug Administration (FDA) to treat relapsed ...

Medically reviewed by Adam M. Brufsky, MD, PhD The exact cause or causes of triple-negative breast cancer are unknown, but ...