precisionmedicineonline1 天
BRCA1/2 Mutations Aren't Equal: Researchers Push for Reduced Penetrance Pathogenic Variant ...
Researchers worked with two labs to identify 16 consensus lower-risk pathogenic variants and are pushing for greater ...
Research shows how even one faulty copy of the BRCA1 gene can fuel breast cancer
People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...
News Medical on MSN4 天
Study sheds light on how BRCA1 gene mutations fuel breast cancer
A new study in mice explains how even a single faulty copy of the BRCA1 gene can fuel tumor growth. The findings suggest the dominant “two-hit” hypothesis of cancer development may not tell the full ...
Armed robbery in Revesby5 天
BRCA1 Gene Mutation's Role in Breast Cancer Uncovered
People inherit two copies of each gene — one from each parent — an evolutionary fail-safe to ensure survival even when one of ...
How BRCA Gene Mutations Impact Breast Cancer Treatment
October is Breast Cancer Awareness Month, and we're teaming up with AstraZeneca to bring you life-saving conversations on ...
Verywell Health on MSN1 年
Causes of Triple-Negative Breast Cancer
Medically reviewed by Adam M. Brufsky, MD, PhD The exact cause or causes of triple-negative breast cancer are unknown, but ...
Medical Xpress6 天
Research shows how even one faulty copy of the BRCA1 gene can fuel breast cancer
Yet women with one harmful BRCA1 mutation are far more likely to develop breast cancer—a risk traditionally explained by a second mutation that arises later in life, damages the healthy copy of ...
Medscape23 天
Differing Clinical Impact of BRCA1 and BRCA2 Mutations in Serous Ovarian Cancer
Pharmacogenomics. 2012;13(13):1523-1535.