Gene therapy involves the introduction of new genes into cells, to restore or add gene expression, for the purpose of treating disease. Most commonly a mutated gene is replaced with DNA encoding a ...

Gene silencing describes the epigenetic regulation of a gene, at the level of transcription or translation, to prevent gene expression. Mechanisms include DNA methylation, histone modification and ...

Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan 48109, United States Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States ...

Here’s how it works. Scientists have discovered a gene variant that could make some parents more likely to have girls than boys. In the new study, researchers analyzed the genomes of around ...

NKX2-3 TF (transcription factor) was a key pancreas EC-enriched signature gene of interest. Motif analysis demonstrated ≈40% of the pancreas EC-enriched signature genes had a DNA-binding motif for ...

"By learning more about how these molecules form and are transported in space, we learn more about our own solar system and so, the life within it." Astronomers have discovered one of the largest ...

1 Queen Mary School, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China 2 School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China ...

Visiting Nassau County on Tuesday, Gov. Kathy Hochul announced plans for the New York BioGenesis Park, a $430 million, 700,000-square-foot cell and gene therapy (CGT) hub in Lake Success.

A crucial molecule for brain health acts as a garbage collector of other fat molecules (lipids), despite also being a lipid itself. So for more than half a century, researchers have puzzled over how ...

LAKE SUCCESS, N.Y.-- Gov. Kathy Hochul on Tuesday announced a $150 million investment in a new state-of-the-art cell and gene therapy hub to be built on Long Island. Coming to the Northwell Health ...

Editas will now focus on a different, newly announced sickle cell program. Like the two sickle cell gene therapies approved last year, Editas’ old program, Reni-Cel, required extracting a ...

A 12-year-old boy has become the first patient in the U.S. to receive gene therapy for sickle cell disease, The New York Times reported Oct. 21. Kendric Cromer began treatment with Bluebird bio's ...