San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted ...

The Arizona Cardinals delivered the dominant offensive performance fans have been craving against the San Francisco 49ers.

The San Francisco 49ers' 2024 season came to an end in a fashion in keeping with a miserable campaign as they suffered defeat ...

The Arizona Cardinals enter the offseason coming off a victory, as they defeated the San Francisco 49ers on Sunday. Here are ...

Check out Kyler Murray's postgame interview after the Arizona Cardinals defeated the San Francisco 49ers in the last game of the regular season.

Jennings got into fights on consecutive plays and fell 25 yards short of a career milestone. But he didn't seem to mind.

The Cardinals earned the No. 16 overall pick in the first round of the 2025 NFL Draft after their season ended with a win ...

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

San Francisco 49ers head coach Kyle Shanahan recapped the team's 47-24 loss to the Arizona Cardinals and evaluated the 49ers overall performance in Week 18.

Former UNC football quarterback Conner Harrell entered the transfer portal in early December with two years of eligibility ...

ARLINGTON, Texas – Trey Lance started at quarterback for the Dallas Cowboys against the Washington Commanders on Sunday, his ...