Organogenesis requires the proper production of diverse cell types and their positioning/migration. However, the coordination of these processes during development remains poorly understood. The gonad ...

We know today that Wnt and a handful of other signalling systems (Notch, Hedgehog, TGFβ (transforming growth factor-β)–BMP (bone morphogenetic protein) and receptor tyrosine kinases ...

In a paper published March 21, 2013, in the journal Science, Nusse and his collaborators show that a protein called Wnt3a coordinates the orientation of the two different cell types that are generated ...

Wnt7a (top) and dystrophin (middle) immunostaining with merged image (bottom) in limb muscles from the mouse model of ALS showed that Wnt7a was within the sarcolemma of muscle fibre in the mouse ...

Our focus is on the Src family tyrosine protein kinases, Hedgehog and Wnt proteins. Petrova E, Rios-Esteves J, Ouerfelli O, Glickman JF, Resh MD. Inhibitors of Hedgehog acyltransferase block Sonic ...

To explore Wnt pathway actions, the researchers focused on how Wnt signals regulate genes, a process mediated by proteins ...