By Dr. Sushama R. Chaphalkar, PhD. By combining advanced gene editing techniques, scientists identified key mutations that ...
Researchers at ETH Zurich combined two CRISPR-Cas methods to decipher how mutations in a cell’s genome affect its function.
【导读】表皮生长因子受体野生型肺腺癌(EGFRWTLUAD)的治疗选择仍然有限,且临床结果不令人满意。据报道,铁死亡作为细胞死亡的一种形式,在调节肿瘤细胞存活中起双重作用。在这项研究中,团队构建了一个3-铁死亡基因特征FeSig,并验证了其预测EGF ...
Lung cancer is the top cause of cancer-related deaths globally, more prevalent in men, and ranks third among women. Both ...
ORIC Pharmaceuticals (NASDAQ: ORIC) is a small-cap pharma stock. It aims to make a difference with its potentially ...
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the ...
If you have non-small-cell lung cancer (NSCLC), your cancer might carry certain changes, or mutations, in your EGFR gene. Those changes make the protein made from this gene act in ways it shouldn’t.
Epidermal growth factor receptor (EGFR) is a protein on the surface of your cells that helps them grow. When the gene that codes for EGFR has a mutation, it affects the way this protein works ...
Two kinase inhibitors have been recommended by the European Medicines Agency for the treatment of non-small cell lung cancer.