The primary focus Patient-Derived Xenograft (PDX) Core is to develop, and provide to the Baylor PDX community, computational and bioinformatics infrastructure to support large scale generation, ...

For example, patient-derived xenograft models, where human tumors are grown in mice, are effective but also slow and expensive. Moreover, they don't fully capture the diversity of interactions ...

Further, treatment with CID-078 increased phosphorylation of separase in sensitive breast cancer patient-derived xenograft (PDX) models. These findings suggest that CID-078 may offer a novel ...