However, as tumors evolve, they exploit the TIME to ... thereby influencing processes like immune escape, angiogenesis, and metastasis. HCC is particularly adept at manipulating the TIME via ...

in an article titled “The UBA1-STUB1 axis mediates cancer immune escape and resistance to checkpoint blockade.” “By screening candidate genes frequently gained in cancer, we identified ...

The immune system plays a pivotal role in colorectal cancer (CRC), with immune cells such as T cells, natural killer (NK) cells, macrophages, and dendritic ...

Millions of individuals are affected by cancer each year. In response, different organizations and the federal government heavily invest in research to dev | Immunology ...

allowing the tumor to escape immune surveillance and rapidly grow. With a mechanism now in hand, the researchers tested whether using TAK-243 to inhibit UBA1 would increase CD8+ recruitment in ...

TACE, while effective in inducing tumor necrosis, exerts dual effects ... are poised to refine the understanding of TME remodeling and immune escape mechanisms. Overcoming technical challenges ...

This therapy is the first to activate specific components of the adaptive immune system, particularly CD4+ T helper cells, which are not known to be involved in traditional cancer treatments.

This study reports the molecular features and interactions of tumor and immune cells associated with two craniopharyngioma subtypes that will help identify future targeted therapeutics.

INR:7491. tip center horse racing Nature: CRISPR discovers 182 potential immunotherapy targets to reveal cancer cells' immune escape Science: Why do anti- ...