Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase ...
Many more signalling proteins are affected in cancer than transcription factors, electing transcription factors as cogent targets. One or more latent cytoplasmic transcription factors (such as ...
Michael Erb, a chemical biologist at Scripps Research and coauthor on the paper, tells C&EN that transcription factors were previously considered undruggable because they “don’t have the types ...