Additionally, all components of the TGF-β Dauer signaling pathway are required for the activation of systemic UPR mt. Further investigations revealed that inhibiting daf-7 function in just a pair ...

Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and ...

3- Kindlin-2 as a major regulator of the oncogenic signaling of TGF-β and cancer cell senescence: We also established Kindlin-2 as a major player in the modulation of the tumor microenvironment by ...

Massagué has been lauded for the originality and importance of his work elucidating the mechanism of action for transforming growth factor-beta (TGF-β) signaling. The TGF-β family of proteins plays a ...

For distinguished contributions to the field of cancer biology, particularly in TGF-beta signaling, and for tireless mentorship and service. The new fellows will receive official recognition during ...

He completed his internal medicine residency and allergy and immunology fellowship at Massachusetts General Hospital. Keros is a clinical-stage biopharmaceutical company focused on developing and ...