Tumor cells circulating in the blood are the "germ cells" of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

there are no therapies that target this critical but understudied step in the progression of cancer." Most metastatic cells ...

Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene. Metastasis is ...

The findings, published in Cell, provide the first evidence of genetic predisposition to breast cancer metastasis, with far-reaching clinical implications—including a potential therapy that ...