In fact, each gene in cellular DNA contains the code for a unique protein structure. Not only are these proteins assembled with different amino acid sequences, but they also are held together by ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

But not all target proteins were receptive to this method, called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not be ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

Researchers have innovatively merged protein structural data with genetic sequences to construct evolutionary trees, ...

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, ...

DZBB resembles a compact cylinder made up of interlocking protein strands. The ancient, origami-like structure can transform ...