Population-based studies report that the majority of elderly patients with heart failure have a normal ejection fraction (HF-NEF) and a history of hypertension. Left ventricular diastolic ...

Figure shows the pathophysiology of heart failure ... In a patient with signs and symptoms of HF, left ventricular dysfunction can be present during systole, diastole, or both.

Heart failure (HF) is a highly prevalent disease ... patients with this type of dysfunction demonstrate a left ventricular (LV) ejection fraction (EF) < 30%. Diastolic dysfunction is seen in ...

Since many of the observed benefits of PDE5 inhibition with regard to left ventricular hypertrophy ... be particularly relevant to the pathophysiology heart failure in patients with preserved ...