However, this company is looking to change the scope of PI3K-alpha [PI3Ka] targeting by going after specific mutation types while sparring wild-type enzyme in healthy human tissues. It believes ...

Enhancing anti-oxidant and anti-inflammatory effects and activating PI3K/Akt were the mechanisms that mediated this effect. Further, GNL treatment upregulated Nrf2 and HO-1 to reduce oxidative ...

In Lag3-mutated Tregs, the scientists found that increased expression of Myc and downstream pathways, including the ...