研究团队表示，如果说导致T细胞衰竭的共抑制受体是“汽车的刹车”，那么乳酸就像是“劣质汽油”，阻碍了汽车的性能。通过阻断MCT11来阻止T细胞获取乳酸，就像是阻止汽车添加劣质汽油，从而帮助提高其性能。阻断了MCT11的T细胞，其共抑制受体的表达并没有差 ...

Programmed cell death-1, or PD-1, has become a headline-grabbing molecule best known for its role in cancer immunotherapies ...

2024年10月17日，清华大学药学院唐海东课题组在《Cell Reports》杂志上发表了题为“PD-L1 protects tumor-associated dendritic cells from ferroptosis during ...

Summit and Akeso's ivonescimab attracted headlines earlier this year when it was shown to be more effective than anti-PD-1 ...

For example, CTLA-4 inhibitors, PD-1 inhibitors and PD-L1 inhibitors ... One main type of immune cell that does this is called a T cell. T cells have proteins on them that turn on an immune response ...

Researchers at Tsukuba University have discovered that the increase in regulatory T (Treg ... Treg cells exhibit altered ...