In the early 20th century, researchers mainly used mice to study cancer. They found that they could only transmit cancer to mice that had a specific mutation but not to animals lacking the mutation.
The newly reported studies demonstrated that the antibodies, in a T cell engager format, can effectively kill cancer cells expressing relevant HER2 mutations both in vitro, and in a mouse ...
Led by scientists from the University of Nottingham in the UK, the study included researchers from Denmark, Greenland, Italy, ...
A study reveals that the immune protein IFITM3 limits flu infection severity and mutation rates, especially from zoonotic ...
Researchers from Congruence Therapeutics Inc. have described the development of a mouse model of genetic obesity with a clinically relevant, naturally occurring human melanocortin MC4 receptor (MC4R) ...
Researchers have identified a protein, TMEM16F, that appears to aid the spread of Parkinson’s pathology in the brain.
A mouse model was used to investigate the functional consequences of the rs374152717 mutation. Mice carrying the human mutation exhibited low bone mass, a hallmark of osteoporosis, which the ...