A study reveals that the immune protein IFITM3 limits flu infection severity and mutation rates, especially from zoonotic ...
The newly reported studies demonstrated that the antibodies, in a T cell engager format, can effectively kill cancer cells expressing relevant HER2 mutations both in vitro, and in a mouse ...
Led by scientists from the University of Nottingham in the UK, the study included researchers from Denmark, Greenland, Italy, ...
Engineered polymers interfere with protein interactions to protect cell health in a mouse study. Researchers at Northwestern University and Case Western Reserve University have developed the first ...
Researchers have identified a protein, TMEM16F, that appears to aid the spread of Parkinson’s pathology in the brain.
Under this two-hit model, Brugge says, one normal copy of BRCA1 ought to be able to carry out DNA repair even when the other ...
For instance, mice with Flvcr1 gene knockouts had severe bone and blood cell development issues that paralleled symptoms of ...
Researchers from Congruence Therapeutics Inc. have described the development of a mouse model of genetic obesity with a clinically relevant, naturally occurring human melanocortin MC4 receptor (MC4R) ...
People inherit two copies of each gene — one from each parent — an evolutionary fail-safe to ensure survival even when one of ...
A new study in mice explains how even a single faulty copy of the BRCA1 gene can fuel tumor growth. The findings suggest the dominant “two-hit” hypothesis of cancer development may not tell the full ...