The pathogens exploit this weak spot: They rapidly colonize the rupture sites and spread into deeper tissue regions. Using human lung organoids, the scientists have been able to elucidate the ...

The development of bronchioalveolar and alveolar organoids is cooperatively induced by FGF10, HGF, and KGF/FGF7. FGF2 and IGF-1 also improve intestinal organoid plating. Sino Biological offers a ...

Generating robust organoids for the lung and gastrointestinal system to recapitulate the complex organ environment remains challenging. Quality growth factors (GFs), such as EGF, FGFs, Noggin, BMP, ...

To address these fundamental questions, we employ a multidisciplinary approach integrating genetic mouse models with lineage-tracing techniques, primary mouse and human lung organoids with genetic ...

Sep. 25, 2024 — Researchers have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive ... A New Ventilator-on-a-Chip ...

Organoids are miniature, high-precision representations of organs, capable of capturing the structure and unique functions of specific organs. Despite the exponential growth of the organoid field ...

In the study, the team created organoids for 12 fetuses with CDH, where the abdominal organs push up into the chest and stop the left lung from growing properly. The condition can be treated while ...

The ability of 3D organoids to self-organize and mimic functional organ cell types is felt to better represent in vivo biology than 2D monolayer cell cultures. As a result, organoids are playing ...

Drug Improves Effectiveness of Radiation for Lung Cancer That Has Spread to the Brain Oct. 4, 2024 — The University of Cincinnati's Debanjan Bhattacharya is first author of new research ...

The study was published in Nature Methods on September 18. Brain organoids are extensively used to study human brain development. Derived from human pluripotent stem cells, the 3D models allow ...