Over the course of just one month in space, engineered human heart tissue got weaker, its ‘beating’ patterns became irregular and it underwent molecular and genetic changes that mimicked the ...
For years, heart research has been limited by a lack of cell models and has relied on animal models to substitute for human hearts, said Elizabeth McNally, MD, Ph.D., the Elizabeth J. Ward ...
In the attempt to calculate the power of the human heart for a given time, we shall arrive at some curious and interesting, not to say astonishing results. Few would credit, at first, the ...
"One of the most surprising findings was how gene regulation in the human heart differs so much from other primates," says Ruiz-Orera. In terms of anatomy, most mammalian hearts are similar.
He and his Ph.D. student at the time, Jonothan Tsui, created the bioengineered heart tissue from human induced pluripotent stem cells (iPSCs). The cells were grown in "organ-on-a-chip" devices ...