BRCA1 acts to channel DNA breaks into HR for repair, Burma said ... Institute to study DNA end resection and DNA break repair pathway choice. The program project, led by Sung, involves Burma ...

Research led by The University of Texas Health Science Center at San Antonio shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes ...

People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...

We found that BRCA1 is important for making sure that this pathway is not used.” A person’s lifetime supply of eggs develops when they’re a fetus, so that’s when fertility problems like ...

The product of a sixth, newly-cloned FA-associated gene has been linked to BRCA1, and may finally offer ... which is correlated with a functional FA pathway. Figure 1: Current view on the Fanconi ...

The presence of BRCA1, BRCA 2 and TP53 genes have been shown to heighten a person’s initial risk of breast cancer. In total, there are about 40 genes shown to increase the risk of developing ...

Cells possess a diversity of sophisticated biological pathways to cope ... Simplified schematic of homologous recombination mechanism. Upon double strand break induction BRCA1 promotes 5 ...

BRCA1 acts to channel DNA breaks into HR for repair, Burma said ... to study DNA end resection and DNA break repair pathway choice, involves Burma as a project leader, and also Eric C.