Ferroptosis offers new strategies to combat treatment resistance in digestive tract cancers, enhancing the efficacy of ...

The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant ...

Research reveals SLC13A3's role in tumor cell survival and immune therapy resistance, highlighting its potential as a target ...

thereby preventing the accumulation of lethal lipid ROS and inhibiting ferroptosis. ② Lipid peroxidation pathway: ACSL4 catalyzes the connection of long-chain polyunsaturated fatty acids to ...

For this, the researchers explored various metabolic pathways. "Ferroptosis is a complex process involving multiple metabolic pathways, including iron metabolism, amino acid metabolism ...

A recent study characterizes the protein interaction landscape for ferroptosis pathways through proteomic analysis, identifies CEPT1 as an LPCAT3-interacting protein, and demonstrates that CEPT1 ...

Ferroptosis and Tumor Treatment Resistance Ferroptosis represents a distinct cell death pathway regulated by iron metabolism, ROS production, and lipid peroxidation. The primary trigger for ...

The treatment of spinal cord injuries has consistently been a focal point of international medical studies, attracting sweeping attention across global research communities. Recent breakthroughs ...

Ferroptosis: necrotic cell death that spreads through cell ... been shown to promote the growth of Ras-mutant pancreatic cancers, and may be an important pathway that drives cancer progression in ...