The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant ...

Ferroptosis offers new strategies to combat treatment resistance in digestive tract cancers, enhancing the efficacy of ...

熊果苷(Arbutin，ARB)是一种从熊果叶中萃取出的成分，具有多种药理活性，包括抗氧化、抗炎和抗菌特性，通常用于化妆品和草药膳食补充剂。 非酒精性脂肪性肝病(NAFLD)是一种潜在的严重疾病，影响全球30%的人口，对人类健康构成重大威胁。近年来，铁死亡作为一种重要的细胞死亡方式，被发现在NAFLD的发生发展中起着关键的调节作用。 2023年11月广西大学的研究者在《Redox Biology》 ...

Research reveals SLC13A3's role in tumor cell survival and immune therapy resistance, highlighting its potential as a target ...

thereby preventing the accumulation of lethal lipid ROS and inhibiting ferroptosis. ② Lipid peroxidation pathway: ACSL4 catalyzes the connection of long-chain polyunsaturated fatty acids to ...

Ferroptosis and Tumor Treatment Resistance Ferroptosis represents a distinct cell death pathway regulated by iron metabolism, ROS production, and lipid peroxidation. The primary trigger for ...

For this, the researchers explored various metabolic pathways. "Ferroptosis is a complex process involving multiple metabolic pathways, including iron metabolism, amino acid metabolism ...

A recent study characterizes the protein interaction landscape for ferroptosis pathways through proteomic analysis, identifies CEPT1 as an LPCAT3-interacting protein, and demonstrates that CEPT1 ...

The treatment of spinal cord injuries has consistently been a focal point of international medical studies, attracting sweeping attention across global research communities. Recent breakthroughs ...

scavenging pathways such as macropinocytosis, and mechanisms of cell death. We investigate cell death mechanisms that have unique effects on cell populations, including entosis that supports the ...