Brown and Goldstein were awarded the Nobel Prize for their outstanding contributions to the study of cholesterol metabolism, including their discovery of receptor-mediated endocytosis. In 1975 ...

This relocation ultimately triggers lipid raft-mediated endocytosis, leading to ingestion of both the CADM1 cluster and the antibodies by the cell. By outlining this mechanism, the researchers ...

Phosphoinositides A class of lipids required for the local recruitment and modulation of signalling factors for endocytosis, actin rearrangement and membrane trafficking. Myosins A large family of ...