In a study led by researchers at the NUS Yong Loo Lin School of Medicine, extracellular vesicles loaded with customizable ...

Epidermal growth factor receptor (EGFR) is a protein on the surface of your cells that helps them grow. When the gene that codes for EGFR has a mutation, it affects the way this protein works ...

The current standard treatment, tyrosine kinase inhibitors (TKIs), targets the mutant EGFR protein but often encounters ...

Researchers at ETH Zurich combined two CRISPR-Cas methods to decipher how mutations in a cell’s genome affect its function.

EGFR, epidermal growth factor receptor, is a protein found on the surface of your cells that makes them grow. If you have non-small-cell lung cancer (NSCLC), your cancer might carry certain ...

"This increased our interest in the epidermal growth factor receptor (EGFR) pathway because previous work indicated that it ...

We computationally designed protein binders for chimeric antigen receptor (CAR) constructs to target the glioblastoma-associated antigens EGFR and CD276. Compared with standard CAR T cells ...

Researchers have used microcellular "drones" to deliver antisense oligonucleotide therapeutics to lung cancer cells.

Resistance to third-generation EGFR-TKIs develops in nearly all patients with EGFR–mutated non–small-cell lung cancer. First-line treatment with amivantamab–lazertinib may improve clinical ...