正常的p53可以形成功能性生物分子凝聚物，而这些突变体则大大加快了向固态、淀粉样状态的转变。这种转变通过一种类似朊病毒（prion）的机制 ...

Our lab has had a long-standing interest in the role and regulation of the p53 tumor suppressor. Mutations in the p53 gene (TP53) are often associated with aggressive tumor behavior and poor patient ...

The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.

The findings were recently published in Communications Chemistry. p53 is central to the body's defense against cancer, tasked with regulating the cell cycle and triggering the death of damaged ...

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The applications for modern day SoCs are becoming bulkier in size, which in turn requires a huge amount of storage. These storage solutions can be On-chip or Off-chip, depending on the system ...