Figure 3: Cytokine signaling in the synovial membrane. As mentioned previously, a broad array of cytokine activities have been described in RA synovia (Box 2). 1 They are usually categorized on ...
Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for ...
Co-opted pathways required by oncogenic KRAS in order to sustain lung tumorigenesis Cytokine signaling and its associated STAT3 and NF-κB activation are required for KRAS-induced tumorigenesis.
Preclinical data demonstrate the ability of p300 KAT inhibition to modulate multiple pro-inflammatory signaling pathways, including antibodies ...