Internet trolls partly aided doctors in diagnosing Amy Schumer with Cushing syndrome, but patients can go years without a diagnosis. Schumer opened up about her February 2024 diagnosis on the “Call Her Daddy” podcast Wednesday, crediting online criticism about her swollen face – a telltale sign of the hormonal disorder.

Cushing syndrome, which is also called Cushing’s syndrome, is a disorder that happens when your body makes too much of the stress hormone cortisol over a long period of time, according to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).