A human intestinal organoid, displaying typical ‘budding crypts’ and a central ‘villus-like’ domain. The main intestinal cell types are shown in green, blue, red and purple. Membranes are ...

Our approach to organoid culture and differentiation involves the use of synthetic matrices to direct morphogenesis through tunable biochemical and mechanical signals. We spatiotemporally pattern ...

and a fluorescent microscopy image of such an organoid. Human intestinal organoid (green) filled with labeled bacteria (blue).

Researchers from the Organoid group at the Hubrecht Institute have developed a new way to grow organoids. Organoids are tiny ...

Intestinal organoids vary in shape and size depending on their stage of development and their complexity. They can range from 200 micrometers at their smallest, or roughly 2.5 times larger than the ...

Key to this research is the use of state-of-the-art human intestinal organoid cultures. Obtained from diverse donors, these cultures provide a physiologically relevant and genetically representative ...

The lab is also interested in the genomic basis of infectious diseases and in understanding how the intestine repairs following infection. The use of intestinal organoid cultures is a foundation for ...

Below are the results from the automation of several typically used organoid protocols, including the culture of 3D organoids in matrix domes. For this study, healthy intestinal organoids were ...

The team coated culture dishes with the enhanced Invasin protein and found that it enabled organoid growth. The coating ...

We offer diverse products and services, including cardiac disease modeling, organoid identification, and drug screening ... our brain organoids enhance understanding and advance disease modeling and ...