Stenoparib is under clinical development by Allarity Therapeutics and currently in Phase I for Colon Cancer. According to GlobalData, Phase I drugs for Colon Cancer have a 56% phase transition success ...
This mutation causes embryonic lethality in the homozygous state. To understand the role of Apc in development, we developed homozygous Apc1638N embryonic stem (ES) cell lines. We examined the ...
[23] The mechanisms that underlie the protective effect of estrogens on colorectal carcinogenesis are not completely understood, although both direct effects on the ERs expressed in colonocytes ...
Estrogens behave as protective agents on the development of colorectal cancer, and hormonal-replacement therapy is associated with an increased survival rate in women with this disease ...