This requires both extravasation of cancer cells from the tumor and ... they are critical steps in the metastatic process that impose significant selective pressure on tumor cells.

Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have ...

Reduced mTOR and amino acid signaling triggers autophagy for cancer cell survival. Autophagic death is attenuated by chemokines in circulation, surviving signaling and possibly other mechanisms.

Their findings will help to develop treatments with which it may be possible to hinder the metastatic process. Cancer is said to metastasize when cells from the primary tumor break off and travel ...

More than half of cancer patients in whom the cancer spreads beyond the primary site have lung metastases. What makes the ...

Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have now uncovered a “genetic signature” of 177 genes shared across multiple ...

Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

Tumor cells circulating in the blood are the “germ cells” of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

An amino acid appears to make the lungs more likely to have cancer spread to them from elsewhere in the body Aspartate ...

New research reveals that ER+ breast cancer cells acquire aggressive characteristics through direct contact with bone marrow ...