Mutations in the adenomatous polyposis coli gene (APC) result in familial adenomatous polyposis (FAP), an autosomal dominant disorder that is marked by susceptibility to gastrointestinal tumours.

APC-deficient mice were treated with 15 cycles ... polyposis - an inherited condition that inevitably leads to colon cancer if the colon is not removed. Treatment of normal tissue caused little ...

Western diets pose a greater risk of Inflammatory Bowel Disease (IBD) and colorectal cancer ... The review was conducted by APC Microbiome Ireland (APC), a world renowned SFI Research Centre ...